13 57% [1, 2]. 2,3%, 1,5%, 1%. 1 2,53% []. .
. . , 8%, , 41%. .
HLA I: HLA13, HLA-B17, HLA-Bw57, HLA-Cw6 [2]. , . HLA', 65% , 2025 .
HLA [I].
Arg/Pro 53 , . , -, [4].
, , , , , .
.
, , .
, - . - ( -) [5, 6] [7, 8], - [9, 10], [II], [12].
- CD4 [5]. , , 1 , - C8,68, CD45R; 1 - 8 [13].
()-8, (-), fCAM-l [14]. - [15]; [16], exjuvantibus 2000 ., , (, -) [16].
Th 1- -
[7,8]. -1 , , [18], -1- [19]. -6,
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